Old Skins Cells Reprogrammed To Regain Youthful Function

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Research from the Babraham Institute has developed a method to ‘time jump’ human skin

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Research from the Babraham Institute has developed a method to ‘time jump’ human skin

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cells by 30 years, turning back the ageing clock for cells without losing their specialised function.

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Work by researchers in the Institute’s Epigenetics research programme has

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been able to partly restore the function of older cells, as well as rejuvenating the

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molecular measures of biological age. The research is published today in the journal eLife

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and whilst at an early stage of exploration, it could revolutionise regenerative medicine.

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What is regenerative medicine?

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As we age, our cells’ ability to function declines and the genome accumulates marks of ageing. Regenerative biology aims to repair

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or replace cells including old ones. One of the most important tools in regenerative biology is our ability to create ‘induced’ stem

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cells. The process is a result of several steps, each erasing some of the marks that make cells specialised.

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