Old Skins Cells Reprogrammed To Regain Youthful Function

Research from the Babraham Institute has developed a method to ‘time jump’ human skin

Research from the Babraham Institute has developed a method to ‘time jump’ human skin

cells by 30 years, turning back the ageing clock for cells without losing their specialised function.

Work by researchers in the Institute’s Epigenetics research programme has

been able to partly restore the function of older cells, as well as rejuvenating the

molecular measures of biological age. The research is published today in the journal eLife

and whilst at an early stage of exploration, it could revolutionise regenerative medicine.

What is regenerative medicine?

As we age, our cells’ ability to function declines and the genome accumulates marks of ageing. Regenerative biology aims to repair 

or replace cells including old ones. One of the most important tools in regenerative biology is our ability to create ‘induced’ stem 

cells. The process is a result of several steps, each erasing some of the marks that make cells specialised.